Desenvolvimento e aplicação de saponáceo à base de óleo de pequi (Caryocar Coriaceum Wittm) na antissepsia da pele de cadelas submetidas à ovariohisterectomia

Abstract

Surgical site infections are significant complications in veterinary medicine, often associated with patient, microbial, and hospital-related factors. The search for safe and accessible therapeutic alternatives has encouraged the use of natural products, which are recognized for their biological properties, low toxicity, and antimicrobial potential. Among these, pequi oil (Caryocar coriaceum Wittm.) is widely used in traditional medicine due to its anti-inflammatory, healing, and antimicrobial actions. This study aimed to develop a saponaceous formulation based on pequi oil and evaluate its efficacy for skin antisepsis in bitches undergoing elective ovariohysterectomy. Nine clinically healthy adult bitches were used, from which skin microbiological samples were collected before and after the application of the antiseptic, using sterile swabs in Brain Heart Infusion (BHI) medium. The samples were analyzed through serial dilutions and colony-forming unit counts after 48 hours of incubation using a colony counter. A reduction in bacterial load was observed in three of the nine samples; however, no significant differences were found between the pre- and post-application evaluations in the remaining animals. It is concluded that the saponaceous formulation, at a 50% concentration, did not demonstrate antimicrobial efficacy.